Drug & Alcohol Rehab Centers in South Carolina
South Carolina offers addiction treatment spanning historic Charleston's coastal clinical programs to Greenville's rapidly growing Upstate treatment corridor, anchored by the Medical University of South Carolina (MUSC) — a national leader in addiction research. With over 210 licensed facilities and strong momentum in expanding access, the state combines coastal and mountain healing environments with genuine Southern community support. MUSC's Center for Drug and Alcohol Programs drives evidence-based innovation, while faith-based programs throughout the state provide spiritual pathways to recovery deeply valued by local communities.
Source: CDC WONDER, SAMHSA NSDUH (2024)
Explore Treatment Centers in South Carolina
Browse 87 treatment facilities across South Carolina on the interactive map
Fetching treatment centers...
Need Help Finding the Right Treatment?
Browse our directory or call to discuss treatment options.
How to Get Started in South Carolina
Call for Help
Call SC HOPE Line at 1-844-724-4673 for a free, confidential conversation about your options.
Get Assessed
A counselor will evaluate your situation and recommend the right level of care. SC Healthy Connections Medicaid can help with referrals.
Verify Coverage
Check your insurance benefits before starting. SC Healthy Connections Medicaid covers substance abuse treatment services.
Begin Treatment
Choose from 210 licensed facilities across South Carolina and start your recovery journey.
All Treatment Centers in South Carolina
Browse and filter facilities
Greenville(8 centers)
Florence(7 centers)
More Cities in South Carolina
50 citiesSigns You May Need Help
Physical Signs
- Needing more of a substance to feel the same effect
- Withdrawal symptoms when not using
- Neglecting physical health and appearance
- Unexplained weight changes
- Sleep pattern disruptions
Behavioral Signs
- Failed attempts to cut down or stop using
- Spending increasing time obtaining, using, or recovering
- Withdrawing from family, friends, and activities
- Continuing use despite negative consequences
- Loss of interest in hobbies and responsibilities
If you recognize these signs in yourself or a loved one, help is available. Call SC HOPE Line at 1-844-724-4673 — 24/7, free, and confidential.
Addiction Treatment in South Carolina
South Carolina's treatment infrastructure centers on three corridors: Charleston offers MUSC-connected clinical excellence and historic coastal treatment environments; Columbia serves as the statewide coordination hub with connections to state resources and diverse urban programs; and Greenville anchors the rapidly growing Upstate treatment market serving the I-85 corridor. MUSC's addiction research programs contribute innovations in pharmacotherapy and behavioral interventions, while community-based facilities across the state provide accessible outpatient care. The state has expanded MAT access and built peer recovery networks, and the DAODAS county authority system ensures every region has a local point of contact for treatment referrals.
- MUSC (Medical University of South Carolina) offers nationally recognized addiction research and treatment programs
- Coastal treatment environments in Charleston and the Lowcountry provide peaceful settings for recovery
- Rapidly growing treatment infrastructure with strong momentum in expanding access and quality
- Lower costs than Northeast and Florida — quality treatment at significantly more affordable rates
- Strong faith-based treatment options integrated with evidence-based clinical approaches
- DAODAS county authority system provides local treatment coordination in every part of the state
SC Healthy Connections Medicaid covers substance abuse treatment services. Many facilities offer financial assistance through DAODAS-funded treatment slots and sliding-scale fees. Private insurers including BlueCross BlueShield of South Carolina and select national plans are accepted statewide. MUSC programs accept most major insurance plans and offer financial counseling for treatment costs.
Types of Treatment Available in South Carolina
| Level | Duration | Setting | Intensity | Cost | Best For |
|---|---|---|---|---|---|
| Medical Detox | 3–7 days | Hospital / Clinic | 24/7 medical | $$$$ | Severe withdrawal, safety |
| Residential | 30–90 days | Live-in facility | Full-time | $$$$ | Serious addiction, structure |
| PHP | 4–6 weeks | Day program | 5–7 hrs/day | $$$ | Step-down, medical needs |
| IOP | 2–4 months | Outpatient center | 3–4 hrs, 3–5x/week | $$ | Working adults, families |
| Outpatient | 3–12 months | Office / Telehealth | 1–2 hrs, 1–2x/week | $ | Maintenance, mild cases |
| Sober Living | 3–12 months | Group housing | Peer support | $$ | Transition, structure |
Medical Detox
$$$$Residential
$$$$PHP
$$$IOP
$$Outpatient
$Sober Living
$$Expert Tips for South Carolina
MUSC in Charleston is a genuine national leader in addiction research — their Center for Drug and Alcohol Programs offers advanced treatment and clinical trial access.
Charleston's treatment environment is unique — historic coastal beauty combined with academic medical excellence creates a compelling recovery setting.
The Greenville Upstate corridor is rapidly expanding treatment options and often has shorter wait times than Charleston programs.
Every South Carolina county has a DAODAS authority — contact yours for local treatment referrals, financial assistance, and waitlist navigation.
The SC HOPE Line (1-844-724-4673) provides 24/7 referrals and can help you find programs with immediate openings.
Faith-based programs in South Carolina are well-established and respected — if spiritual support matters to your recovery, you'll find excellent options here.
Official state resources and organizations providing addiction treatment support in South Carolina.
SC Department of Alcohol and Other Drug Abuse Services (DAODAS)
State agency managing substance abuse prevention, treatment, and recovery services across South Carolina
1-803-896-5555SC HOPE Line
24/7 crisis support and treatment referral helpline for substance use and mental health
1-844-724-4673National Resources
Federal resources and hotlines available 24/7 for addiction support.
Free, confidential, 24/7, 365-day-a-year treatment referral and information service
Find treatment facilities in your area
Provides 24/7 free and confidential support for people in distress
Research and information on drug use and addiction
Frequently Asked Questions
This website provides general information about addiction treatment centers. It is not a substitute for professional medical advice, diagnosis, or treatment. If you're in crisis, call 988 (Suicide & Crisis Lifeline) or 911. For help finding treatment, call SAMHSA at 1-800-662-4357 — free, confidential, 24/7.
Information sourced from SAMHSA Treatment Locator, state licensing records, and facility submissions.